Chapter 25: Cannabinoids and Pain: Clinical Evidence
Authors: MacCallum CA, Eadie L & Narouze SN
In this chapter, we have summarized systematic reviews of randomized controlled trials using cannabis-based medicine for pain, including but not limited to chronic pain (non-cancer pain, neuropathic pain, centralized pain disorders such as fibromyalgia, rheumatic inflammatory pain, cancer pain) and acute pain.
It appears that more consistent methodology is needed among future research designs with regard to cannabis product, dosing, method of intake, timing of administration, pain scale measurements, and how pain is subjectively measured and reported. Without this, it is challenging to compare the breadth of data that now exists on cannabis and its effect on pain.