This page contains research articles and infographics pertaining to cannabis use for pain and opioid reduction. The role of medical cannabis in treatment of chronic pain, and recent clinical evidence to support it can be found here. The use of cannabis as an adjunctive treatment to prevent opioid escalation, and entourage opioid therapy shows promise, and is outlined step-by-step.

Chapter 25
Cannabinoids and Pain: Clinical Evidence

Narouze SN, MacCallum CA. eds. Cannabinoids and Pain. Springer; 2021

Chapter 27
Cannabinoids as a Substitute for Opioids: Basic Science and Clinical Evidence

Narouze SN, MacCallum CA. eds. Cannabinoids and Pain. Springer; 2021

Systematic Review
Cannabidiol as a Harm Reduction Strategy for People Who Use Drugs: A Rapid Review
The Canadian Journal of Psychiatry. 2023

Lo L… MacCallum CA, et al.

Colloquium
The Role for Medical Cannabis in Chronic Pain Management

Bell A… MacCallum C… et al., EnsembleIQ; 2018